La Habana, Cuba. Methods: prospective, longitudinal, descriptive and observational study of 62 patients 65 anophthalmic cavities who went to the Oculoplasty service of "Ramon Pando Ferrer" Cuban Institute of Ophthalmology from May to December Age, sex, causes of eye loss, affected eye, conjunctival disease, type of cavity, length of time of prosthesis use, microbiological result, hygienic handling and response to treatment were the analyzed variables. Conclusions: conjunctival diseases in patients with ocular prosthesis are a health problem. Similarly, most of the anophthalmic cavities are atypical in adults with loss of eyeball from traumatism. Allergic conjunctivitis and conjunctival retraction are the most frequent illnesses in the patients wearing ocular prosthesis for more than one year, due to Staphylococcus aureus presence resulting from frequent hygienic handling of the prosthesis.

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Saornil M. Universidad de Valladolid. Palabras clave: Tumores conjuntivales, neoplasia intraepitelial, nevus, melanoma, linfoma. Conjunctival tumors are one of the most frequent of the eye and adnexa. They comprise a large variety of conditions, from benign lesions such as nevus or papiloma, to malignant lesions such as epidermoid carcinoma or melanoma which may threaten visual function and the life of the patient. They can arise from any cellular component, but the most frequent are of epithelial and melanocytic origin.

Early diagnosis is essential for preventing ocular and systemic spread and to preserve visual function. In this paper we review the clinical characteristics of the most frequent conjunctival tumors, and we discuss tumor management Arch Soc Esp Oftalmol ; Key words: Conjunctival tumors, intraepithelial neoplasia, nevus, melanoma, lymphoma.

Papiloma escamoso. Hiperplasia pseudoepiteliomatosa o pseudocarcinomatosa. Puede evolucionar a carcinoma escamoso de conjuntiva, aunque es raro fig.

El termino CIN conjunctival intraepithelial neoplasia , incluye los distintos grados de displasia leve, moderada y grave fig. B: Carcinoma in situ de conjuntiva. Hiperplasia epitelial con displasia que se extiende a todas las capas del epitelio HE10x. Carcinoma escamoso. Carcinoma escamoso fusiforme.

Los estudios immunohistoquimicos positivos para citoqueratinas, confirman la naturaleza epitelial de este tumor Carcinoma Mucoepidermoide. Son raros y suelen aparecer en ancianos. Los objetivos del tratamiento de los tumores de conjuntiva son:. Comprenden un espectro de alteraciones que abarcan desde lesiones benignas como el nevus de conjuntiva hasta condiciones malignas, potencialmente letales, como el melanoma de conjuntiva. Se mueven libremente sobre la esclera y no se extienden sobre la cornea.

Melanocitosis ocular. Melanosis Adquirida secundaria. No predisponen al desarrollo de melanoma. Nevus con atipia. Melanosis Adquirida primaria MAP. Cuando la conjuntiva del borde palpebral se afecta, se extiende a menudo a la epidermis adyacente. Una vez que se presenta la enfermedad diseminada, no existe tratamiento eficaz y los pacientes tienen un tiempo de supervivencia relativamente corto. Incluso, deben realizarse biopsias en zonas aparentemente no involucradas debido a la presencia de MAP sine pigmento.

Se debe evitar realizar biopsias incisionales. En el seguimiento, los pacientes deben ser cuidadosamente revisados en la consulta, explorando la superficie entera de la conjuntiva exhaustivamente y palpando los ganglios preauriculares y cervicales. Sarcomas, fibromas, neurofibromas, schwanomas, neurotekiomas.

Se presenta como una masa sonrosada elevada de crecimiento lento en personas mayores 1, Su tratamiento consiste en la biopsia escisional 4. Sarcoma de Kaposi. B: Celularidad fusiforme con numerosas hendiduras capilares HE40x.

A: Masa asalmonada subconjuntival infiltrativa que afecta fondo de saco, conjuntiva tarsal. Tumors of the eye and ocular adnexa. Tumors of the conjunctiva and cornea.

Surv Ophthalmol ; Spectrum of conjunctival tumors in an ocular oncology unit: review of cases. Acta Ophthalmol Scand ; S Frequency of melanocytic conjunctival lesios in an ocular oncology unit. Conjunctival and corneal pathology. Principles and practice of ophthalmology. Philadelphia: WB Saunders Co. Cibis GW. Basic and Clinical Science Course. Section 2. San Francisco: American Academy of Ophthalmology; ; Knop N, Knop E.

Conjunctiva-associated lymphoid tissue in the human eye. Invest Ophthalmol Vis Sci ; Grossniklaus HE. Section 4. Actinic keratosis and dysplasia of the conjunctiva: a clinicopathological study of 45 cases. Can J Ophthalmol ; Factors associated with conjunctival intraepithelial neoplasia: a case control study.

Ophthalmic Surg ; Human papillomavirus 16 and 18 expression in conjunctival intraepithelial neoplasia. Ophthalmology ; Topical mitomicyn C for the treatment of conjunctival and corneal epithelial dysplasia and neoplasia. Am J Ophthalmol ; Chemotherapy for eye cancer. Treatment of conjunctival and corneal intraepithelial neoplasia with topical interferon alpha-2b.

Topical interferon or surgical excision for the management of primary ocular surface squamous neoplasia. Empleo de interferon Alfa-2B para el tratamiento de carcinomas conjuntivales intraepiteliales en casos seleccionados.

Arch Soc Esp Oftalmol ; Escleroqueratitis y carcinoma escamoso conjuntival invasivo. Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases. Br J Ophthalmol ; Seregard S, Kock E. Squamous spindle cell carcinoma of the conjunctiva. Fatal outcome of a plerygium-like lesion. Acta Ophthalmol Scand ; Surgical management of conjunctival tumors. The Lynn B. McMahan Lecture. Arch Ophthalmol ; Surgical management of ocular surface squamous neoplasms.

The experience from a cornea center. Cornea ; Damato B. Ocular Tumors. Diagnosis and treatment. Oxford: Butterworth Heineman; Antimetabolites in ocular surface neoplasia. Curr Opin Ophthalmol ; 9: Clinicopathologic characteristics of premalignant and malignant melanocytic lesions of the conjunctiva.

Ophthalmology ; 96 Clinical survey of melanocytic and nonmelanocytic conjunctival tumors. Benign conjunctival melanocytic lesions. Clinicopathologic features. Lifetime prevalence of uveal melanoma in white patients with oculo dermal melanocytosis. Conjunctival melanosis and melanoma. Seregard S. Conjunctival melanoma.


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