The number of people that have oral herpes is vastly higher. The herpes virus is almost always transmitted through skin to skin contact sexual or nonsexual and results in periodic flare-ups of painful or itching blisters and sores around the mouth, face and genital regions. These are sometimes accompanied by fever and other symptoms of infection, particularly during the initial exposure. Most physicians and scientists say that herpes is incurable because they have not yet found a vaccine or other treatment that effectively controls or destroys the virus. The best that they can offer has been complicated, difficult-to follow diets that help keep the virus in its latent inactive state, ointments that merely ease some of the symptoms, and a new generation of toxic, marginally effective acyclovir-like drugs that interfere with DNA transcription both viral and human.
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The number of people that have oral herpes is vastly higher. The herpes virus is almost always transmitted through skin to skin contact sexual or nonsexual and results in periodic flare-ups of painful or itching blisters and sores around the mouth, face and genital regions.
These are sometimes accompanied by fever and other symptoms of infection, particularly during the initial exposure. Most physicians and scientists say that herpes is incurable because they have not yet found a vaccine or other treatment that effectively controls or destroys the virus.
The best that they can offer has been complicated, difficult-to follow diets that help keep the virus in its latent inactive state, ointments that merely ease some of the symptoms, and a new generation of toxic, marginally effective acyclovir-like drugs that interfere with DNA transcription both viral and human.
DNA is like a computer code that translates into words in an encyclopedia. Other animals have different numbers of chromosomes. The DNA in chromosomes is extremely long. A typical human chromosome contains 50 to million nucleic acids strung together in a chain. This extremely long strand of DNA strand is wound around a protein core called a histone very much like the way thread is wound around a spool.
Viral DNA is much smaller. Viral genomes are only thousand nucleotides long. They are extremely small because much of the biochemical machinery that they need in order to replicate is provided by the host cell.
When virus DNA inserts itself into the cell, it is copied transcribed, translated repeatedly into RNA, like a Zerox machine making multiple photocopies. Only with viral DNA, you get viral proteins. Other viruses simply accumulate in the infected cell to the point where the cell eventually ruptures and is destroyed, spewing forth thousands to millions of new viruses into the blood stream where they travel to infect new cells.
If this viral life cycle continues unchecked, the virus will multiply until it either causes serious organ pathology or it kills enough cells to kill its host.
Fortunately, the immune system counteracts this process by detecting the virus proteins and destroying infected cells and free viruses. Scientists call herpes a lipid-enveloped virus because of the fat lipid found in the outer shell or coat. To the immune system, lipid-enveloped viruses look more like tiny fat droplets than an infectious organism.
Not all viruses are lipid enveloped. For example, poliomyelitis polio virus, hepatitis A and the common cold virus rhinovirus have no lipid covering their outer protein shell. There is not yet any clear evidence yet that suggests that BHT has an effect on non-lipid viruses.
However, there has been medical reporting over many decades that antibiotic use seems to result in beneficial effects in viral disease, even though there is no known mechanism! Standard vaccination approaches for lipid-viral diseases become difficult-to-impossible because they are based on the immune system's response to proteins. Lipid-enveloped viral diseases are among the most difficult diseases to treat. Currently identified lipid viruses include all herpes strains, Epstein-Barr virus, human immunodeficiency virus HIV, all strains , cytomegalovirus CMV , hepatitis viris B and C , rubella virus German measles , varicella virus chicken pox , Newcastle disease virus, swine fever virus, SARS virus, West Nile virus, and influenza virus all strains, including bird flu virus.
Virus that successfully evades the immune system retreats through nerve fibers to nerve clusters ganglia near the brain or spinal cord, where they go into a latent state. Sometimes, the virus will remain in this state for life, causing no apparent harm.
In many cases however, it is awakened periodically by changes in body chemistry due to stress, diet, illness, weakened immune system, menstruation, overexposure to sunlight, or other causes. Even sexual activity can trigger the dormant virus to become active. The virus then travels from the ganglia, through the nerve fibers, back to the same area that it first affected and the victim has another episode of sores and blisters. These eventually subside as the virus retreats once more to its hiding place in the ganglia, where it remains until it is triggered again into its active state.
First, it disrupts the virus's lipid envelope, leaving it naked and vulnerable to attack by the immune system. Second, it removes binding proteins that viruses need to bind to and penetrate cell membranes.
Without these binding proteins, viruses are non-infective. Whether or not these mechanisms are applicable to living animals has not been determined. In fact, it may be near to impossible to make that determination.
They can then study whether whole viruses disintegrate in response to an antiviral agent. This is not the case with lab animals suffering from a viral infection. The viral replication process the assembly line is not particularly efficient. There are many more viral parts produced that there are fully assembled viruses. Massive numbers of viral fragments are released when an infected cell ruptures. Scientists cannot easily distinguish between viral fragments that are a natural product of inefficient viral replication and viral fragments that are produced by BHT disruption of intact viruses.
So in real-life, we haven't yet figured out how BHT works. Despite these unanswered questions, researchers have found that BHT does interfere in the course of lipid-enveloped viral diseases.
Animals given BHT resolve their lipid-enveloped viral diseases much faster than otherwise. And people using BHT do experience relief from their herpes infections. Empirically, it works. BHT is not a cure for herpes.
Once infected, the herpes virus inserts itself into our DNA and becomes, essentially, a part of our genes. BHT does not change that. No known technology can yet change that. BHT may even be able to block herpes infection in the first place—and reinfection in people already infected—if used prophylactically. Coohill, Michael Babich, William D.
The plaque development of Herpes simplex virus type 1 HSV is slower for viruses treated with two anti-DNA agents: ultraviolet radiation UV or n-acetoxyacetyl-aminofluorene. For HSV treated with three anti-membrane agents -butylated hydroxytoluene, acridine plus near UV radiation, or ether-the plaque development time is the same as for untreated viruses.
Gamma ray inactivation of HSV produces no change in plaque development even though this agent is believed to preferentially affect viral DNA. All rights reserved. Several factors have been investigated which are of significance in the inactivation of PM2, a lipid-containing bacterial virus, by butylated Hydroxytoluene BHT. Studies of the time dependence of inactivation during exposure to BHT showed that virus killing occurs rapidly, with the majority of the effect taking place in the first 5 min.
The degree of inactivation is dependent upon the initial virus titer, the solvent from which BHT is added, and the presence of a variety of protective agents, including surfactants, bovine serum albumin, and bacterial cells. These experiments show that the 32P-labeled molecules are converted into very slowly sedimentable material by BHT treatment, indicating complete destruction of the virus particle.
The viral envelope is not removed by BHT treatment, in contrast to the effects of exposure to the detergent Triton X BHT-treated viruses are morphologically indistinguishable from controls but are defective in their ability to attach to the host cell. Temperature at the time of exposure was found to. A precipitous drop in the degree of inactivation by 3 x M BHT occurred when the temperature was lowered from 20 to 15 C. Calcium ions were found to potentiate the effect of BHT, particularly at lower temperatures where BHT alone was relatively ineffective.
Barium and strontium, but not magnesium, were also effective in enhancing the activity of BHT. Both BHT and BHA are commonly used as food additives, have apparent low toxicity to humans and other animals, and are potentially useful as antiviral agents. Dennis H. Prog Clin Biol Res , Studies with a hydrophobic, spin-labeled virucidal agent. Antimicrob Agents Chemother 17 1 : , Jan Eletr, M.
Williams, T. Watkins and A. Perturbations of the dynamics of lipid alkyl chains in membrane systems: Effect on the activity of membrane bound enzymes. Biochim Biophys Acta , Snipes, S. Person, A. Keith, and J. Cupp, Science, Vol. Butylated hydroxytoluene protects chickens exposed to Newcastle disease virus.
Science , p , Orally administered butylated hydroxytoluene inhibits herpes simplex virus type I infection in rabbits. Some effects of phenolic anti- oxidants on sodium and potassium balance in the rabbit.
British Journal of Experimental Pathology, Vol 38 5 , p , Fisherman EW and Cohen G. Chemical intolerance to butylated- hydroxyanisole BHA and butylated-hydroxytoluene BHT and vascular response as an indicator and monitor of drug intolerance. Ann Allergy 31 3 , p , March Franklyn RA. Butylated hydroxytoluene in sarcoma-prone dogs.
The Lancet, p , June 12, Treatment of recurrent herpes simplex labialis with topical butylated hydroxytoluene.
Clinical Pharmacology and Therapeutics 38, p , Ito N. Critical Reviews In Toxicology 15 2 p , Keith AD, Arruda D.
BHT and the silent epidemic...Herpes
A little over 25 years ago a paper got published in the journal Science showing that BHT Butylated hydroxytoluene , a common food preservative, could inactivate herpes simplex and other lipid-coated viruses in lab dishes. Two years later another paper in the same journal reported similar results, but this time in live animals—dietary BHT could prevent chickens from dying of Newcastle disease. Like herpes simplex, NDV the virus that causes Newcastle disease is lipid-enveloped, i. Viruses of this type require an intact membrane to be infective. In the chicken study cited above, the amount of BHT needed to inhibit NDV turned out to be equal to the amount already present in chicken feed as an additive, i.
Wipe Out Herpes
Dear Dr. I am very intrigued by what I read on your website. Thank you. Thanks for the honorary doctorate! I do not know whether this reply is a duplicate.
Eradication of Persistent Herpes
About BHT. Steven Wm. Fowkes has dedicated the last 35 years to researching the mysteries behind the herpes virus. Mann and Steven Wm. Fowkes and staff of the MegaHealth Society. I have included some excerpts from his book. All rights reserved.
My name is Domenic. I have a serious question. I wrote to this e-mail address hoping you would receive it. I have had many outbreaks of herpes. I also have a couple of friends who also suffer from this depressing ailment.